Thoughts on these defects please?  

Additional info

This is a MK3S+ printer, overture PETG, my temp settings are right where they were previously (240 first layer, 250 after that).  

One more thing

One last thing lol, I have two printers, I attempted the print on both and the defect remains, so it's not the printer, it's the gcode.  

Thanks 🙂

Try slowing down and observe the effect

Are the ones with the defect on the left rotated from those with it on the right?

The simplest troubleshooting step is always to slow down. Try dialing the speed back 50% using the front knob. Does the defect reduce or go away? If so, you know it's something you can fix with slicer settings. You might also look at retraction and z-seam positioning.

Slowing down

Slowing down does help.   All 4 boxes were oriented on the plate in the same position.   I dont think those particular layers even have a seam, since there is a gap in the perimeter of the cube.   The "seam" would be the notch itself, no?

I'll keep messing with it.  I got off an acceptable print for now just slowing it down.   But I just wish I knew what the issue was, as I was able to print these consistently at 200% before I wiped out my slicer install.  🙁

Live and learn.   I'll for sure not make that mistake again (not saving settings). 

Export config bundle, try reducing MVS

Do yourself a favor and export a config bundle with all your customized presets (File->Export->Export config bundle) regularly.

If slowing down helped, you might try reducing the Maximum volumetric speed setting for that filament (Filament Settings->Advanced). Rather than manually changing a bunch of speeds in your otherwise good print settings, this will set an upper throttle to keep flows below a specific rate just for that specific filament.

Are you getting the defects also when using the stock, unmodified Generic PETG profile? If not, you can compare the parameters sections of the gcodes generated by your profile and the stock profile to see what settings were modified by your custom profile. 

The defects look way too big to be z-seam. 

And other suspects such as temperature, extrusion width issues, clogs, etc I wouldn't expect to be so location specific. 

RE: Prettu much factory settings now

Right now, this is basically the stock Prusament PETG profile.   I don't think I have changed anything at all in the filament profile yet. 

Printer profile, I just added some custom heating gcode that helps with oozing during MBL (Heat to 175/85, wait for bed, MBL, then heat to first layer temp.   I also do an extended pre-print wipe, across the entire plate.  I think that's about it there. 

Ugh.... 🙁  I'll be exporting setting weekly or so now, just in case of another unexpected windows 10 event....

Old G-Code?

@twoballscrewball

Do you have some g-code left from "the good days"? Old g-code from before reinstalling windows.
If so, you can retrieve settings from them

I do have old g-codes

I do have old G-codes.  How do I pull settings out of those?

Open the gcode file in a text editor, then look at the end of the gcode file. There's a long list of comments (lines that start with a semicolon) that describe each parameter.

E.g.:

; filament used [mm] = 10850.61
; filament used [cm3] = 26.10
; filament used [g] = 33.15
; filament cost = 1.20
; total filament used [g] = 33.15
; total filament cost = 1.20
; estimated printing time (normal mode) = 1h 45m 33s

; avoid_crossing_perimeters = 1
; avoid_crossing_perimeters_max_detour = 0
; bed_custom_model = 
; bed_custom_texture = 
; bed_shape = 0x0,180x0,180x180,0x180
; bed_temperature = 90

etc.

Perfect

@twoballscrewball 

Perfect 👍 

Either, as said, Notepad, or you can import them in Prusaslicer.
"File" -> "Import" -> "Import Config" -> choose a *.gcode-file you know works.
All settings from that file will now be imported to "Print-" "Filament-" and "Printer Settings"